Some Data

Lack of Regulation of the Modification-Dependent Restriction Enzyme McrBC in Escherichia coli.
Mark Murphy, 2002.Restriction alleviation (RA) by the type I restriction enzyme EcoKI is caused by treatments that damage DNA . RA is due to proteolysis of the EcoKI HsdR subunit by the ClpXP ATP-dependent protease . Here we show that the modification-dependent enzyme McrBC is not subject to RA, although it is moderately sensitive to ClpAP .

Identification, Timing, and Signal Specificity of Pseudomonas aeruginosa Quorum-Controlled Genes: a Transcriptome Analysis.
Martin Schuster, 2003.There are two interrelated acyl-homoserine lactone quorum-sensing-signaling systems in Pseudomonas aeruginosa . These systems, the LasR-LasI system and the RhlR-RhlI system, are global regulators of gene expression . We performed a transcriptome analysis to identify quorum-sensing-controlled genes and to better understand quorum-sensing control of P . aeruginosa gene expression . We compared gene expression in a LasI-RhlI signal mutant grown with added signals to gene expression without added signals, and we compared a LasR-RhlR signal receptor mutant to its parent . In all, we identified 315 quorum-induced and 38 quorum-repressed genes, representing about 6% of the P . aeruginosa genome . The quorum-repressed genes were activated in the stationary phase in quorum-sensing mutants but were not activated in the parent strain . The analysis of quorum-induced genes suggests that the signal specificities are on a continuum and that the timing of gene expression is on a continuum (some genes are induced early in growth, most genes are induced at the transition from the logarithmic phase to the stationary phase, and some genes are induced during the stationary phase) . In general, timing was not related to signal concentration . We suggest that the level of the signal receptor, LasR, is a critical trigger for quorum-activated gene expression . Acyl-homoserine lactone quorum sensing appears to be a system that allows ordered expression of hundreds of genes during P . aeruginosa growth in culture .

What Is Genome?, What Is Prokaryote?, What Is Botulism?, What Is Biotechnology?, What Is Pcr?, c, Microorganism, o, Bacterium, a, Bacteria, n, Microbe, s, Microorganisms, a, Escherichia coli, a, Escherichia coli, n, Botulism, s, Salmonella, e, Yeasts, r, Neisseria, e, Microbial

Scientific Publications - Work Done by Microbiology Reader Bioscreen C
Agricultural Microbiology Anaerobic Microbiology Antimicrobial Susceptibility Artificial Atmosphere Bioassay of Antibiotics Biofilm Microbiology Bioreactor Technology Biotechnology Cell Biology Clinical Microbiology Environmental Microbiology Experiments with Yeast	Fermentation Food Microbiology Functional Genomics Gene Technology Growth Media Development Growth Rate and Lag Time Industrial Microbiology Medical/Pharmaceutical Field Microbiological Assay Microbiological Research Microbiology of Cosmetics go to a specific theme...	Military Microbiology Molecular Microbiology Mutagenicity and Genotoxicity Oral Microbiology Patents Postantibiotic Studies Soil Microbiology Spore Microbiology Veterinary Microbiology Waste/Wastewater Treatment Water Microbiology Wine Microbiology

© 2005 Transgalactic Ltd (manufacturer of Bioscreen C software) | Privacy Statement | P.O. Box 1393, 00101 Helsinki, Finland, phone: +358 9 85172920, fax: +358 9 8749481, e-mail: microbiology@bionewsonline.com

Last modified: May 25, 2005