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Scientific
Publications - Work Done by Microbiology Reader
Okubo, T., Suzuki, T., Fujita, K., Iyobe, S. and Inoue, M., Postantibiotic
effects (PAE's) of macrolide antibiotics evaluated using ABSTRACT Postantibiotic effects (PAE's) of macrolide antibiotics were
determined for Staphylococcus aureus and Enterococcus faecalis using viable
counting and Bioscreen C method and the two methods were compared. No major
differences between the two methods were observed. The Bioscreen C method was
less laborious than the viable counting. The durations of PAE for S. aureus
following exposures to erythromycin (EM), josamycin (JM) and rokitamycin (RKM)
for 2 hours at twice the MICs were in ranges of 0.85 to 1.45, 2.36 to 3.48 and
1.93 to 5.45 hours, respectively. A definite PAE of 1.0 to 5.8 hours was also
observed in E. faecalis strains exposed for 2 hours to EM, JM and RKM at twice
the MICs.
(order Full Text from publisher)
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