Scientific Publications - Work Done by Microbiology Reader Bioscreen C

Lindl, T., Pellkofer, R. and Englert, K., [In-vitro test for toxicity of diethylene glycol by use of cell culture systems and an automated bacterial test system], In-vitro-Toxizitätsuntersuchungen von Diethylenglykol mittels Zellkulturen und einem automatisierten Bakterientestsystem, (Ger.), Zeitschrift fur Lebensmittel-Untersuchung und-Forschung, 1986, vol. 183, pp. 1-7

ABSTRACT

Diethyleneglycol was tested for its general cytotoxic effects in three cell culture test systems and in a novel, automated bacterial test system. The first cytotoxic effects were detected in the cell culture test systems at DEG-concentrations of 1 g/1 and 3g/1. The bacterial test system showed a minimal inhibitory concentration of 5 g/1 DEG (20% growth reduction). Morphological observations showed evidence of membrane damage to the cultured cells by DEG. With the bacterial test system one could determine the amount of DEG semiquantitatively in wines to which this material had been added.

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Last modified: May 25, 2005