Scientific Publications - Work Done by Microbiology Reader Bioscreen C

Jang, Ki-Chang; Kim, Seong-Cheol; Song, Eun-Young; Kim, Kong-Ho; Kwon, Hyeog-Mo; Kang, Sang-Heon; Park, Ki-Hun; Jung, Yong-Hwan, Isolation and structure identification of antibacterial substances from the rhizome of Zingiber mioga Roscoe, Han'guk Nonghwa Hakhoechi (2003), 46(3), 246-250, ISSN: 0368-2897 [Journal written in Korean]

ABSTRACT

In order to isolate antibacterial substances from the rhizome of Zingiber mioga Roscoe, the ethanol exts. was fractionated according to the activity against Bacillus subtilis, B. cereus and Staphylococcus aureus. Three antibacterial substances were isolated and purified by column chromatog. and recrystn. Compds. I and III showed activity against all the tested bacterias and compd. II exhibited the activity against B. subtilis and B. cereus except S. aureus. Compd. I was examd. antimicrobial activity against B. subtilis, B. cereus and S. aureus by optical d. using Bioscreen C. Compd. I showed strong growth inhibition at 10 ppm on B. subtilis and B. cereus for 72 h, and at 25 ppm on S. aureus. On the basis of spectrometric studies including 1H-NMR, 13C-NMR, DEPT, 1H-1H COSY, HMQC, HMBC and IR, compds. I, II and III were identified as (E)-8ß(17)-epoxylabd-12-ene-15,16-dial (C20H30O3, MW=318), galanolactone (C20H30O3, MW=318) and galanal A (C20H30O3, MW=318), resp. These results are the first reports on the isolation of (E)-8ß(17)-epoxylabd-12-ene-15,16-dial, galanolactone and galanal A from the rhizome of Zingiber mioga.

(order Full Text from publisher)

© 2005 Transgalactic Ltd (manufacturer of Bioscreen C software) | Privacy Statement | P.O. Box 1393, 00101 Helsinki, Finland, phone: +358 9 85172920, fax: +358 9 8749481, e-mail: microbiology@bionewsonline.com
 

Last modified: May 25, 2005